Name the largest city on the eastern shore of Lake Ontario.

The largest city on the eastern shore of Lake Ontario is Kingston. It has a significant historical and strategic importance due to its location at the mouth of the St. Lawrence River, connecting to the Great Lakes. Kingston served as the first capital of the Province of Canada and is known for its vibrant waterfront, historic architecture, and educational institutions, such as Queen's University.

Oswego, while also located on the eastern shore, is smaller than Kingston and does not have the same level of city services or population. Syracuse, although a larger city, is situated further inland in New York State and not directly on the shore of Lake Ontario, while Brockville is smaller in terms of population and city status compared to Kingston.