The main vessel route from the St Lawrence River and Toronto lies _____?

The main vessel route from the St. Lawrence River to Toronto indeed lies between Point Petrie and west of Great Duck Island. This route is crucial for navigating the waters safely and efficiently due to its deeper channels, allowing for larger vessels to transit without the risk of grounding on shallower shoals or in less navigable areas.

This pathway is well-established and frequently used, making it essential for commercial and recreational boating traffic. The geographical features in this area, including the positioning of the islands and shallows, help define the safest and most reliable navigational course. Knowledge of these specific locations is critical for mariners to avoid hazards and to ensure safe passage from the St. Lawrence River region to Toronto.

The other options refer to different locations that do not provide the same navigational safety or are not recognized as the primary route for vessels traveling between these two points.